Pertussis Toxin from Bordetella pertussis (lyophilized, salt free)

CAT N°: 23221
Price:

619.00 526.15

Pertussis toxin was first isolated from B. pertussis and is used to study G protein-coupled receptor signaling in cells and experimental autoimmune encephalomyelitis (EAE) in animals. Pertussis toxin catalyzes the transfer of the ADP-ribose moiety of NAD to the ? subunits of heterotrimeric Gi/o proteins, resulting in the receptors being uncoupled from Gi/o proteins.{31502,31505} Pertussis toxin is also used as an adjuvant, given with specific antigens, to immunize animals and induce EAE, an animal model of multiple sclerosis.{31260,31504}

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