(+)-PD 128907 (hydro<wbr/>chloride)

(+)-PD 128907 (hydrochloride)

CAT N°: 21235
Price:

From 48.00 40.80

(+)-PD 128907 is a potent agonist of the dopamine 3 (D3) receptor (Ki = 1 nM).{33953,33956} It shows selectivity for D3 over D2 and D4 receptors (Kis = 1.2 and 7 µM, respectively).{33953} Low doses of (+)-PD 128907 (13 µg/kg, s.c.) reduce spontaneous locomotor activity in rats.{33954} It blocks stereotypy induced by the NMDA receptor antagonist (+)-MK-801 (Item No. 10009019) in mice.{33957} (+)-PD 128907 is used in animal models to study the role of the D3 receptor in nervous system disorders, such as schizophrenia, Parkinson’s disease, and depression.{31907,33955}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 3,4,4aR,10bR-tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol, monohydrochloride
  • Correlated keywords
    • 123671-92-1 PD128907 PD-128970 PD128970 D-3 n-methyl-D-aspartic MK801
  • Product Overview:
    (+)-PD 128907 is a potent agonist of the dopamine 3 (D3) receptor (Ki = 1 nM).{33953,33956} It shows selectivity for D3 over D2 and D4 receptors (Kis = 1.2 and 7 µM, respectively).{33953} Low doses of (+)-PD 128907 (13 µg/kg, s.c.) reduce spontaneous locomotor activity in rats.{33954} It blocks stereotypy induced by the NMDA receptor antagonist (+)-MK-801 (Item No. 10009019) in mice.{33957} (+)-PD 128907 is used in animal models to study the role of the D3 receptor in nervous system disorders, such as schizophrenia, Parkinson’s disease, and depression.{31907,33955}

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