24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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€231.00 €196.35
€231.00 €196.35
Protectin conjugates in tissue regeneration 1 (PCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid (DHA; Item No. 90310).{38180} DHA is oxidized to 16S,17S-epoxy-protectin, which is then converted to PCTR1 by glutathione S-transferase.{38180,38178} PCTR1 levels increase during resolution of acute microbial-induced peritonitis in mice.{38179} PCTR1 (30 ng, i.p.) administration 12 hours post-infection increases macrophage numbers and activity and shortens the resolution phase of inflammation by 57%. It also reduces the levels of PGE2 (Item No. 14010), PGD2 (Item No. 12010), and TXB2 (Item No. 19030) in peritoneal exudates.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 10 µg, 100 µg, 25 µg, 50 µg |
|---|---|
| Shipping | dry ice |
| CAS number | 1810710-59-8 |
| Molecular formula | C32H47N3O9S |
| Smiles | CC/C=CC[C@H](O)[C@H](SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@@H](C(O)=O)N)=O)/C=C/C=C/C=CC/C=CC/C=CCCC(O)=O, CC/C=CC[C@H](O)[C@H](SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@@H](C(O)=O)N)=O)/C=C/C=C/C=CC/C=CC/C=CCCC(O)=O, CC/C=CC[C@H](O)[C@H](SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@@H](C(O)=O)N)=O)/C=C/C=C/C=CC/C=CC/C=CCCC(O)=O, CC/C=CC[C@H](O)[C@H](SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@@H](C(O)=O)N)=O)/C=C/C=C/C=CC/C=CC/C=CCCC(O)=O |
| Molecular weight | 649,8 |
| Custom code | 2922.19 |
| Formulation | A solution in ethanol |
| Purity | ≥96% |
| UNSPSC code | 12352100 |
Cayman Chemical’s mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.
Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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