PAF Acetyl<wbr>hydrolase (human, recombinant)

PAF Acetylhydrolase (human, recombinant)

CAT N°: 10279
Price:

724.00 615.40

Platelet-activating factor (PAF) is an important lipid mediator involved in inflammation. PAF-acetylhydrolase (PAF-AH) is an extracellular phospholipase A2 which hydrolyzes the acetyl group at the sn-2 position of phospholipids.{2618} Two main types of PAF-AH have been characterized, namely the secreted (i.e. plasma) and intracellular enzymes, which are encoded on individual genes and share only 41% homology at the amino acid level.{4758,6501} Cayman’s PAF-AH is the secreted calcium-independent isoform. PAF deacetylation by PAF-AH causes loss of biological activity, making PAF-AH potentially useful as an anti-inflammation therapy.

Territorial Availability: Available through Bertin Technologies only in France

  • Correlated keywords
    • proteins PAFs lipids mediator inflammation PAFAH enzymes PAF AH phospholipases PLA2s inflammatory N-terminal His-tags His-tagged active ferroptosis
  • Product Overview:
    Platelet-activating factor (PAF) is an important lipid mediator involved in inflammation. PAF-acetylhydrolase (PAF-AH) is an extracellular phospholipase A2 which hydrolyzes the acetyl group at the sn-2 position of phospholipids.{2618} Two main types of PAF-AH have been characterized, namely the secreted (i.e. plasma) and intracellular enzymes, which are encoded on individual genes and share only 41% homology at the amino acid level.{4758,6501} Cayman’s PAF-AH is the secreted calcium-independent isoform. PAF deacetylation by PAF-AH causes loss of biological activity, making PAF-AH potentially useful as an anti-inflammation therapy.

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