ONO-4059

ONO-4059

CAT N°: 32957
Price:

163.00 138.55

ONO-4059 is an inhibitor of Bruton’s tyrosine kinase (BTK; IC50 = 2.2 nM).{30642} It is selective for BTK over LCK, LYN, and Fyn at 1 µM.{59933} ONO-4059 inhibits B cell proliferation and activation in vitro and reduces tumor growth in a TMD8 mouse xenograft model.{30642,59932}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 6-amino-7,9-dihydro-9-[(3R)-1-(1-oxo-2-butyn-1-yl)-3-pyrrolidinyl]-7-(4-phenoxyphenyl)-8H-purin-8-one
  • Correlated keywords
    • 1639851-93-6 1881234-05-4 2086736-37-8 ONO4059 GS4059 ONOWG307 WG307 TMD
  • Product Overview:
    ONO-4059 is an inhibitor of Bruton’s tyrosine kinase (BTK; IC50 = 2.2 nM).{30642} It is selective for BTK over LCK, LYN, and Fyn at 1 µM.{59933} ONO-4059 inhibits B cell proliferation and activation in vitro and reduces tumor growth in a TMD8 mouse xenograft model.{30642,59932}

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