Oleoyl Serotonin

Oleoyl Serotonin

CAT N°: 9000629
Price:

From 74.00 62.90

Oleoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin (Item No. 70665). Arachidonoyl serotonin is a dual antagonist of fatty acid amide hydrolase (FAAH) and the transient receptor potential vanilloid type 1 (TRPV1) channel, reducing both acute and chronic peripheral pain.{18121,18122} Oleoyl Serotonin inhibits capsaicin-induced TRPV1 channel activation (IC50 = 2.57 ?M) without blocking FAAH-mediated hydrolysis of arachidonoyl ethanolamine (IC50 > 50 ?M).{18121}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-9Z-octadecenamide
  • Correlated keywords
    • N-arachidonoyl serotonin AA-5-HT AA-5HT antagonists fatty acids amide hydrolase FAAH transient receptors potential vanilloid-type 1 channels TRPV1 pain capsaicin ethanolamine anandamide AEA Hydrolase Long-Chain Fatty-Acyl-CoA Fatty-Acyl-CoA Hydrolase Long-Chain Long-Chain Fatty-Acyl-CoA Hydrolase Long Chain Fatty Acyl CoA Hydrolase Palmitoyl Coenzyme A Hydrolase Acylhydrolase Oleoyl-CoA Thioesterase Fatty Acyl Oleoyl-CoA Acylhydrolase Oleoyl CoA Acylhydrolase Hydrolase Palmitoyl-CoA Deacylase, Palmitoyl CoA CoA Deacylase, Palmitoyl Thioesterase, Palmitoyl Palmitoyl-CoA Hydrolase Palmitoyl CoA Hydrolase Palmitoyl CoA Deacylase Hydrolase Stearoyl CoA Fatty Acyl Thioesterase CoA Hydrolase Stearoyl Stearoyl CoA Hydrolase Palmitoyl Thioesterase Hydrolase Acyl CoA CoA Hydrolase Acyl Acyl CoA Hydrolase Thioesterase I
  • Product Overview:
    Oleoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin (Item No. 70665). Arachidonoyl serotonin is a dual antagonist of fatty acid amide hydrolase (FAAH) and the transient receptor potential vanilloid type 1 (TRPV1) channel, reducing both acute and chronic peripheral pain.{18121,18122} Oleoyl Serotonin inhibits capsaicin-induced TRPV1 channel activation (IC50 = 2.57 ?M) without blocking FAAH-mediated hydrolysis of arachidonoyl ethanolamine (IC50 > 50 ?M).{18121}

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