Amyloid-? (1-8, A2V) Peptide
Amyloid-? (1-8, A2V) Peptide
Amyloid-? (1-8, A2V) is a truncated form of amyloid-? (A?) that contains a valine to alanine substitution at position 2...
€114.00
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From €85.00 €72.25
From €85.00 €72.25
Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases. This cell permeable inhibitor targets the multiple isoforms of PP1 (IC50 = 10-50 nM), both isoforms of PP2A (IC50 = 0.5 nM) and PP3 (IC50 = 4 nM).{21676,21677,21678} It is a very weak inhibitor of PP2B (IC50 > 2 ?M) and does not inhibit PP2C or other phosphatases.{21676,21678} Presumably through these actions, okadaic acid is a potent carcinogen and induces tau phosphorylation.{21680,21681} In sponge, okadaic acid plays a role in defense, inducing apoptosis in symbiotic or parasitic annelids.{21679}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 100 µg, 25 µg, 50 µg |
|---|---|
| Shipping | dry ice |
| CAS number | 78111-17-8 |
| Molecular formula | C44H68O13 |
| Smiles | OC([C@](C)(O)C[C@H]1[C@@H](O)CC[C@@]2(OC([C@H](C)/C=C/[C@@H]3O[C@]4(CCC(O[C@H]([C@@H](O)C[C@H](C)[C@H]5O[C@@]6(CCCCO6)CC[C@H]5C)C([C@H]7O)=C)C7O4)CC3)CC(C)=C2)O1)=O |
| Molecular weight | 805 |
| Custom code | 2932.99 |
| Formulation | A solution in ethanol |
| Purity | ≥95% |
| UNSPSC code | 12352100 |
Cayman Chemical’s mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.
Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.
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