Ochratoxin A

Ochratoxin A

CAT N°: 11439
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Ochratoxin A (OTA) is a mycotoxin that has been found in Aspergillus and Penicillium.{21687} It increases lipid peroxide levels and the number of apoptotic cells, as well as reduces superoxide dismutase activity in rat kidney when administered at a dose of 120 ?g/kg.{57301} Topical application of ochratoxin A (80 ?g/mouse) induces DNA damage, cell cycle arrest at the G0/G1 phase, and apoptosis in mouse skin cells.{21687} It also initiates tumor formation in a two-stage mouse skin tumorigenesis model. Ochratoxin A has been found as a contaminant in a variety of foods.{21686}

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