Norursodeoxy<wbr/>cholic Acid

Norursodeoxycholic Acid

CAT N°: 33925
Price:

From 109.00 92.65

Norursodeoxycholic acid (norUDCA) is a bile acid and the C23 homolog of UDCA (Item No. 15121).{54967,54966} Unlike UDCA, norUDCA does not undergo conjugation to taurine or glycine and is secreted in an unchanged form, as trihydroxy derivatives, or as sulfate or glucuronide conjugates. Dietary administration of norUDCA (0.5% w/w) decreases serum levels of alanine aminotransferase (ALT) and alkaline phosphatase, markers of cholestasis, periductal fibrosis, and hepatic hydroxyproline content in an Mdr2-/- mouse model of sclerosing cholangitis.{54967}

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