Nocodazole

Nocodazole

CAT N°: 13857
Price:

From 55.00 46.75

Nocodazole reversibly binds tubulin and alters tubulin-associated GTP hydrolysis as well as microtubule dynamics.{22044,21248} While nocodazole is used to study many aspects on microtubule function, it is most commonly used to synchronize cell cycling in culture.{22043,22042} Typically, nanomolar concentrations of nocodazole reduce both microtubule elongation and shortening velocities, resulting in arrest of cycling in a G2/M phase.{22045,22043} Nocodazole is also used to induce the formation of Golgi ministacks in eukaryotic cells.{21248}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-[6-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid, methyl ester
  • Correlated keywords
    • 59697-13-1 NSC238159 NSC-238159 R17934 R-17934 microtubules cytoskeleton cells cycling mitosis cancera division synchronization binds binding tubulin GTP hydrolysis elongation shortening velocities G2/M phase Golgi ministacks eukaryotic
  • Product Overview:
    Nocodazole reversibly binds tubulin and alters tubulin-associated GTP hydrolysis as well as microtubule dynamics.{22044,21248} While nocodazole is used to study many aspects on microtubule function, it is most commonly used to synchronize cell cycling in culture.{22043,22042} Typically, nanomolar concentrations of nocodazole reduce both microtubule elongation and shortening velocities, resulting in arrest of cycling in a G2/M phase.{22045,22043} Nocodazole is also used to induce the formation of Golgi ministacks in eukaryotic cells.{21248}

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