(–)-Nicotine (tartrate)

(–)-Nicotine (tartrate)

CAT N°: 20887
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(?)-Nicotine is the dominant form of the natural alkaloid nicotine.{26727} It acts as an agonist of neuronal nicotinic acetylcholine receptors (nAChRs) and possesses addictive and teratogenic properties.{18814} (?)-(S)-Nicotine is significantly more active at binding nAChRs compared to the (+)-(R) antipode, thus nicotine is typically synthesized as (?)-(S)-nicotine with only 0.2-1% of the (+)-(R) isomer present.{26727}

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