Nicaraven

Nicaraven

CAT N°: 23482
Price:

From 48.00 40.80

Nicaraven is an antioxidant that exhibits hydroxyl radical scavenging activity in vitro.{36261} Nicaraven (1-3 mg/kg per min, i.v.) reduces occurrence of chronic cerebral vasospasms in a dose-dependent manner in a canine model of subarachnoid hemorrhage. In a canine model of warm hepatic ischemia and reperfusion injury, nicaraven (2 mg/kg per min, i.v.) reduces liver enzyme release and inhibits lipid peroxidation and neutrophil infiltration in the liver.{36262} Nicaraven (100 mg/kg per day, i.p.) also decreases plasma levels of the inflammatory cytokines Il-6 and Tnf-? and the urinary levels of 8-oxo-2′-deoxyguanosine, a marker of DNA oxidation, in a mouse model of radiation-induced injury.{36263}

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