N<sup>1</sup>-<wbr/>Acetylspermidine (hydro<wbr>chloride)

N1–Acetylspermidine (hydrochloride)

CAT N°: 9001535
Price:

From 92.00 78.20

N1-Acetylspermidine is an acetyl derivative of spermidine (Item No. 14918) that acts as a substrate for polyamine oxidase (PAO).{26260} In peroxisomes, PAO oxidizes N1-acetylspermidine to 3-acetamidopropanal and putrescine, a positively charged polyamine that binds DNA and is involved in various cellular processes including cell division, differentiation, and membrane function.{26259,23742,23743,12989} N1-Acetylspermidine has been used to examine the interaction between DNA and polyamines during the cleavage of phosphodiester bonds at apurinic/apyrimidinic sites in DNA.{27034}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-[3-[(4-aminobutyl)amino]propyl]-acetamide, dihydrochloride
  • Correlated keywords
    • substrate polyamine oxidase PAO peroxisomes 3-acetamidopropanal putrescine cell division differentiation DNA cleavage apurinic apyrimidinic endonucleases AP sites DNA repair 14278-49-0 34450-16-3 120205-20-1 polyamines oxidases PAOs peroxisomes membranes functions HCl biology enzymes dihydrochloride
  • Product Overview:
    N1-Acetylspermidine is an acetyl derivative of spermidine (Item No. 14918) that acts as a substrate for polyamine oxidase (PAO).{26260} In peroxisomes, PAO oxidizes N1-acetylspermidine to 3-acetamidopropanal and putrescine, a positively charged polyamine that binds DNA and is involved in various cellular processes including cell division, differentiation, and membrane function.{26259,23742,23743,12989} N1-Acetylspermidine has been used to examine the interaction between DNA and polyamines during the cleavage of phosphodiester bonds at apurinic/apyrimidinic sites in DNA.{27034}

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