N-Nitroso Metoprolol

N-Nitroso Metoprolol

CAT N°: 34738
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From 66.00 56.10

N-Nitroso metoprolol is a genotoxic derivative of metoprolol (Item No. 15429).{60686,58696} It induces DNA fragmentation in rat hepatocytes when used at concentrations ranging from 0.1 to 1 mM.{60686} In vivo, N-nitroso metoprolol (1,000 mg/kg) induces micronucleation of rat hepatocytes but not erythrocytes from the bone marrow or spleen.

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