N-Desmethylclobazam (CRM)

N-Desmethylclobazam (CRM)

CAT N°: 18888
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N-Desmethylclobazam (CRM) (Item No. 18888) is a certified reference material that is structurally categorized as a benzodiazepine. It is a major active metabolite of clobazam, produced primarily by the action of cytochrome P450 isoform 3A4.{31385} N-Desmethylclobazam (CRM) positively modulates GABAA receptors (EC50s range from 98 to 151 µM, depending on subunit configuration).{31386} This product is intended for research and forensic applications.

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