N-Acetyl-L-aspartic Acid

N-Acetyl-L-aspartic Acid

CAT N°: 34635
Price:

From 182.00 154.70

N-Acetyl-L-aspartic acid is an acetylated form of L-aspartic acid.{63202} It is formed from L-aspartate and acetyl-CoA (Item No. 16160) by L-aspartate N-acetyltransferase (Asp-NAT) in neuronal mitochondria.{63203} N-Acetyl-L-aspartic acid is hydrolyzed to L-aspartate and acetate by aspartoacylase (ASPA), which is expressed by oligodendrocytes. N-Acetyl-L-aspartic acid levels are increased in the brain of patients with Canavan disease, an autosomal recessive disorder caused by loss-of-function ASPA mutations and characterized by cognitive and motor impairments.{63204,63203,63202}

We also advise you