Muristerone A

Muristerone A

CAT N°: 11741
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From 85.00 72.25

Muristerone A is a natural analog of 20-hydroxyecdysone (Item No. 16145). It is an agonist of the ecdysteroid receptor (Kd = 1 nM), a nuclear receptor that heterodimerizes with a retinoid X receptor ortholog and regulates arthropod development.{26923,26924,26920} Muristerone A is used as an agonist in ecdysone-inducible gene expression systems in mammalian cells.{26921,26316} However, it inhibits apoptosis in the human colon carcinoma cell line RKO by inducing the upregulation of Bcl-xL, suggesting limitations in its use in certain types of studies.{26922}

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