Histone H2A (Xenopus, recombinant)
Histone H2A (Xenopus, recombinant)
Histone H2A is a core histone that forms a dimer with histone H2B.{46631} Two histone H2A/H2B dimers form an octameric...
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€136.00 €115.60
€136.00 €115.60
Morusin is a prenylated flavonoid that has been found in M. alba and has diverse biological activities, including enzyme inhibitory, anti-inflammatory, and antiproliferative properties.{52095,52094,52093,59092} It inhibits the UDP-glucuronosyltransferase (UGT) isoforms UGT1A6, UGT1A7, and UGT1A8 (IC50s = 4.23, 0.98, and 3 ?M, respectively) and the cytochrome P450 (CYP) isoforms CYP3A4, CYP1A2, CYP2C9, and CYP2E1 (IC50s = 2.13, 1.27, 3.18, and 9.28 ?M, respectively).{52095} Morusin (4 ?M) inhibits histamine and leukotriene C4 (LTC4) production induced by A23187 (Item No. 11016) and phorbol 12-myristate 13-acetate (PMA; Item No. 10008014) in mouse MC/9 mast cells.{52094} It also inhibits the growth of MCF-7, MDA?MB?231, and MDA?MB?453 breast cancer cells (IC50s = 13.53, 10.84, and 11.99 ?M, respectively).{52093} Morusin (12.5 mg/kg per day) decreases colonic tissue damage, TGF-?1 levels, and matrix metalloproteinase-2 (MMP-2) and MMP-9 activity in a rat model of TNBS-induced ulcerative colitis.{59092}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 10 mg, 5 mg, 50 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 62596-29-6 |
| Molecular formula | C25H24O6 |
| Smiles | OC1=CC=C(C(OC2=C3C(O)=CC4=C2C=CC(C)(C)O4)=C(C/C=C(C)/C)C3=O)C(O)=C1 |
| Molecular weight | 420,5 |
| Custom code | 2907.19 |
| Formulation | A solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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