24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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MLR-1023 is an allosteric activator of Lyn kinase (EC50 = 63 nM).{34026} It has no significant activity against a panel of related kinases. MLR-1023 is orally bioavailable and reduces blood glucose levels in mice subjected to an oral glucose tolerance test.{34026} This effect is insulin-dependent, with MLR-1023 increasing insulin receptor sensitivity.{34025} MLR-1023 produces a dose-dependent and durable glucose-lowering effect in chronically treated db/db mice without causing weight gain.{34025}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 10 mg, 25 mg, 5 mg, 50 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 41964-07-2 |
| Molecular formula | C11H10N2O2 |
| Smiles | CC1=CC=CC(OC2=CN([H])C(N=C2)=O)=C1 |
| Molecular weight | 202,2 |
| Custom code | 2922.19 |
| Formulation | A crystalline solid |
| Purity | ≥95% |
| UNSPSC code | 12352100 |
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