MLCK Inhibitor Peptide 18

MLCK Inhibitor Peptide 18

CAT N°: 19181
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From 48.00 40.80

MLCK inhibitor peptide 18 is a cell-permeable inhibitor of myosin light chain kinase (MLCK; IC50 = 50 nM) with 4,000-fold selectivity for MLCK over CaM kinase II and PKA.{31132,31133} It prevents defects in transepithelial barrier resistance induced by bacteria or TNF-? plus IFN-?.{31133} MLCK inhibitor peptide 18 prevents sperm chromatin-induced cortical reorganization in mouse oocytes and decreases phagocytosis of C3bi-opsonized and non-opsonized myelin by primary mouse microglia.{31130,31131}

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