ML-309 (hydro<wbr/>chloride)

ML-309 (hydrochloride)

CAT N°: 21519
Price:

From 59.00 50.15

ML-309 is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH1).{42529} It reversibly and selective inhibits IDH1R132H over wild-type IDH1 (IC50s = 96 and 36,500 nM, respectively). ML-309 reduces 2-hydroxyglutarate production in U87 MG glioblastoma cells (EC50 = 55 nM).

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-[2-(cyclopentylamino)-1-(2-methylphenyl)-2-oxoethyl]-N-(3-fluorophenyl)-1H-benzimidazole-1-acetamide, monohydrochloride
  • Correlated keywords
    • 1355446-05-7 ML309 IDH-1 isocitrate dehydrogenase 1 R132H U87MG WT
  • Product Overview:
    ML-309 is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH1).{42529} It reversibly and selective inhibits IDH1R132H over wild-type IDH1 (IC50s = 96 and 36,500 nM, respectively). ML-309 reduces 2-hydroxyglutarate production in U87 MG glioblastoma cells (EC50 = 55 nM).

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