MitoP-d<sub>15</sub>

MitoP-d15

CAT N°: 19296
Price:

From 102.00 86.70

MitoP-d15 is intended for use as an internal standard for the quantification of MitoP (Item No. 17117) by GC- or LC-MS. MitoP is a phenol product produced by the reaction of H2O2 with the ratiometric mass spectrometry probe MitoB (Item No. 17116). MitoB contains a triphenylphosphonium cation component that drives its accumulation in mitochondria where its arylboronic moiety selectively reacts with H2O2 to produce MitoP.{27786,27787} Quantifying the MitoP/MitoB ratio by LC-MS/MS reflects the mitochondrial matrix H2O2 concentration.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • [(3-hydroxyphenyl)methyl]triphenyl-d5-phosphonium, monobromide
  • Correlated keywords
    • 742016-83-7 74597-01-6 H2O2 MS probe mitochondrial matrix mito-P mito-B phenol ratio-metric triphenyl-phosphonium mito-phenol deuterated deuterium GC-MS GC/MS gases chromatography masses spectrometry LC-MS LC/MS liquid isotope GCMS LCMS hydrogen peroxide
  • Product Overview:
    MitoP-d15 is intended for use as an internal standard for the quantification of MitoP (Item No. 17117) by GC- or LC-MS. MitoP is a phenol product produced by the reaction of H2O2 with the ratiometric mass spectrometry probe MitoB (Item No. 17116). MitoB contains a triphenylphosphonium cation component that drives its accumulation in mitochondria where its arylboronic moiety selectively reacts with H2O2 to produce MitoP.{27786,27787} Quantifying the MitoP/MitoB ratio by LC-MS/MS reflects the mitochondrial matrix H2O2 concentration.

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