Minocycline (hydro<wbr>chloride hydrate)

Minocycline (hydrochloride hydrate)

CAT N°: 14454
Price:

From 48.00 40.80

Minocycline is a broad-spectrum tetracycline antibiotic.{66121} It is active against E. faecium in vitro (MIC = 16 mg/L). Minocycline (20 mg/kg every 12 hours) reduces the number of bacteria in the lung in a mouse model of multidrug resistant A. baumannii-induced pneumonia.{66122} It reduces spinal cord lesion size and improves hindlimb function post-injury in a mouse model of acute spinal cord injury when administered at an initial dose of 50 mg/kg and subsequent doses of 25 mg/kg per day for 5 days.{66123} Formulations containing minocycline have been used in the treatment of acne vulgaris.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (4S,12aS)-4,7-bis(dimethylamino)-1,4,4aS,5,5aR,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide, monohydrochloride, hydrate
  • Correlated keywords
    • 10118-90-8 11006-27-2 150231-24-6 1071702-75-4 1236362-29-0 13614-98-7 anti-biotics NSC141993 Enterococcus Acinetobacter multi-drug
  • Product Overview:
    Minocycline is a broad-spectrum tetracycline antibiotic.{66121} It is active against E. faecium in vitro (MIC = 16 mg/L). Minocycline (20 mg/kg every 12 hours) reduces the number of bacteria in the lung in a mouse model of multidrug resistant A. baumannii-induced pneumonia.{66122} It reduces spinal cord lesion size and improves hindlimb function post-injury in a mouse model of acute spinal cord injury when administered at an initial dose of 50 mg/kg and subsequent doses of 25 mg/kg per day for 5 days.{66123} Formulations containing minocycline have been used in the treatment of acne vulgaris.

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