MEK1 (Phospho-Thr292) Polyclonal Antibody

CAT N°: 10009518
Price:

680.00 578.00

MAP kinase kinase 1 (MAPKK1) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation {14328,14329}. This pathway also plays a key role in synaptic plasticity in the brain {14327}. Activated MEK1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase {14331,14332,14543}. Conversely, there also appears to be a feedback phosphorylation of MEK1 by MAP kinase. The sites on MEK1 that are phosphorylated by MAP kinase on Thr292 and Thr386 {14330}.

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