From €231.00 €196.35
Maresin conjugates in tissue regeneration 1 (MCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid (DHA; Item No. 90310) in macrophages at the site of inflammation.{29715,33727} DHA is oxidized to maresin 1 (MaR1; Item No. 10878), which is then converted to MCTR1 by glutathione S-transferase Mu 4 or leukotriene C4 synthase.{27629,33713,27956} MCTR1 accelerates tissue regeneration in planaria (1 and 100 nM).{33727} Pretreatment with MCTR1 (50 ng/mouse, i.p.) prior to E. coli administration reduces neutrophil infiltration, shortens the inflammatory resolution period, and increases phagocytosis of E. coli by macrophages.{33727} When administered at a dose of 100 ng 12h post E. coli infection in a mouse model of peritonitis, MCTR1 reduces the amount of eicosanoids in the exudate.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 10 µg, 100 µg, 25 µg, 50 µg |
|---|---|
| Shipping | dry ice |
| CAS number | 1784701-61-6 |
| Molecular formula | C32H47N3O9S |
| Smiles | O[C@@H](C/C=CC/C=CCC)[C@H](SC[C@H](NC(CC[C@H](N)C(O)=O)=O)C(NCC(O)=O)=O)/C=C/C=C/C=CC/C=CCCC(O)=O, O[C@@H](C/C=CC/C=CCC)[C@H](SC[C@H](NC(CC[C@H](N)C(O)=O)=O)C(NCC(O)=O)=O)/C=C/C=C/C=CC/C=CCCC(O)=O, O[C@@H](C/C=CC/C=CCC)[C@H](SC[C@H](NC(CC[C@H](N)C(O)=O)=O)C(NCC(O)=O)=O)/C=C/C=C/C=CC/C=CCCC(O)=O, O[C@@H](C/C=CC/C=CCC)[C@H](SC[C@H](NC(CC[C@H](N)C(O)=O)=O)C(NCC(O)=O)=O)/C=C/C=C/C=CC/C=CCCC(O)=O |
| Molecular weight | 649,8 |
| Custom code | 2930.90 |
| Formulation | A solution in ethanol |
| Purity | ≥95% |
| UNSPSC code | 12352100 |
Cayman Chemical’s mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.
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Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.
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