Madrasin

Madrasin

CAT N°: 20451
Price:

From 48.00 40.80

Madrasin is a cell-permeant inhibitor of pre-mRNA splicing.{34068} It interferes with the early stages of spliceosome assembly and stalls spliceosome assembly at the A complex.{34068} Madrasin induces cell cycle arrest, promotes a specific reorganization of subnuclear protein localization, and modulates splicing of multiple pre-RNA species in both HeLa and HEK293 cells when used at lower concentrations.{34068}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2-[(7-methoxy-4-methyl-2-quinazolinyl)amino]-5,6-dimethyl-4(3H)-pyrimidinone
  • Correlated keywords
    • DDD00107587 HEK-293 premRNA preRNA DDD-00107587
  • Product Overview:
    Madrasin is a cell-permeant inhibitor of pre-mRNA splicing.{34068} It interferes with the early stages of spliceosome assembly and stalls spliceosome assembly at the A complex.{34068} Madrasin induces cell cycle arrest, promotes a specific reorganization of subnuclear protein localization, and modulates splicing of multiple pre-RNA species in both HeLa and HEK293 cells when used at lower concentrations.{34068}

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