Lysipressin (acetate)

Lysipressin (acetate)

CAT N°: 37430
Price:

From 83.00 70.55

Lysipressin is a peptide hormone found in pigs and marsupials that corresponds to amino acids 20-28 of the vasoconstrictor peptide vasopressin with lysine in place of arginine at position 27.{38886,38887} It is an arginine vasopressin receptor 1A (V1A) receptor agonist that binds to rat and human V1A receptors (Kis = 1.2 and 10.1 nM, respectively) and increases intracellular calcium levels in cultured rat and human aortic cells with half-maximal activation (Kact) values of 12 and 20.8 nM, respectively.{47419} Lysipressin induces vasoconstriction in isolated mesenteric arteries from normotensive and spontaneously hypertensive rats.{62862} It also has antidiuretic effects in non-anesthetized dwarf pigs, decreasing urine volume and increasing urinary solutes without affecting the glomerular filtration rate.{38886}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 8-L-lysine-vasopressin, monoacetate
  • Correlated keywords
    • 50-57-7 ?24218 24218 anti-diuretic nonanesthetized
  • Product Overview:
    Lysipressin is a peptide hormone found in pigs and marsupials that corresponds to amino acids 20-28 of the vasoconstrictor peptide vasopressin with lysine in place of arginine at position 27.{38886,38887} It is an arginine vasopressin receptor 1A (V1A) receptor agonist that binds to rat and human V1A receptors (Kis = 1.2 and 10.1 nM, respectively) and increases intracellular calcium levels in cultured rat and human aortic cells with half-maximal activation (Kact) values of 12 and 20.8 nM, respectively.{47419} Lysipressin induces vasoconstriction in isolated mesenteric arteries from normotensive and spontaneously hypertensive rats.{62862} It also has antidiuretic effects in non-anesthetized dwarf pigs, decreasing urine volume and increasing urinary solutes without affecting the glomerular filtration rate.{38886}

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