LY2157299

LY2157299

CAT N°: 15312
Price:

From 74.00 62.90

LY2157299 is a small molecule inhibitor of the TGF-? receptor type 1 kinase (IC50 = 56 nM).{24957} It has been used to study the role of TGF-? signaling in chemotherapy-induced expansion of cancer stem-like cells in triple negative breast cancer cell lines and xenografts.{24958} LY2157299 has also been shown to inhibit the migration and tumor growth of hepatocellular carcinoma cell lines by disrupting Smad-2 phosphorylation.{24959}

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