LP44 (hydro<wbr>chloride)

LP44 (hydrochloride)

CAT N°: 17287
Price:

From 66.00 56.10

LP44 is a full agonist of the serotonin 5-HT7 receptor (Ki = 0.22 nM) that displays 200- and greater than 1,000-fold selectivity over 5-HT1A (Ki = 52.7 nM) and 5-HT2A (Ki = 326 nM) receptors, respectively.{28320} It can induce relaxation of substance P-induced guinea pig ileum contraction with an EC50 value of 2.56 ?M.{28320}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 4-[2-(methylthio)phenyl]-N-(1,2,3,4-tetrahydro-1-naphthalenyl)-1-piperazinehexanamide, monohydrochloride
  • Correlated keywords
    • 826337-01-3 agonist serotonin 5-HT7 receptor smooth muscle relaxation neuroscience biochemical intracellular signaling signal transduction neurochemical 5HT7 selective LP-44 relaxation substance P-induced guinea pig ileum contraction
  • Product Overview:
    LP44 is a full agonist of the serotonin 5-HT7 receptor (Ki = 0.22 nM) that displays 200- and greater than 1,000-fold selectivity over 5-HT1A (Ki = 52.7 nM) and 5-HT2A (Ki = 326 nM) receptors, respectively.{28320} It can induce relaxation of substance P-induced guinea pig ileum contraction with an EC50 value of 2.56 ?M.{28320}

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