Lauric Acid Leelamide

Lauric Acid Leelamide

CAT N°: 10008618
Price:

From 91.00 77.35

Lauric acid leelamide is the lauric (C-12) amide analog of leelamine. Leelamine has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 µM.{14127} Leelamine inhibits pyruvate dehydrogenase kinase (PDHK) with an IC50 value of 9.5 µM.{14105} Derivatives of leelamine exhibit anti-inflammatory activity and show moderate inhibition of phospholipase A2 activity from a variety of sources.{14107} There are no published studies of the pharmacological properties of lauric acid leelamide.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 1R,2,3,4,4aS,9,10,10aR-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrene-dodecanamide
  • Correlated keywords
    • saturated fatty acids synthesized synthesis plants animals acetyl coenzymes CoA energy storage 12-carbons coconut nut oils COX-2 cyclooxygenase-2 cyclooxygenases expressions C:8-18 inhibitors inhibits inhibition pyruvate dehydrogenases kinases diterpene Sanskrit CB1 CB2 cannbinoids receptors central peripheral tertiary 3H CP55940 PDK antiinflammatory anti-inflammatory PLA2 phospholipases inflammation dehydroabietylamine leelamine cannabinoids cbs synthetic
  • Product Overview:
    Lauric acid leelamide is the lauric (C-12) amide analog of leelamine. Leelamine has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 µM.{14127} Leelamine inhibits pyruvate dehydrogenase kinase (PDHK) with an IC50 value of 9.5 µM.{14105} Derivatives of leelamine exhibit anti-inflammatory activity and show moderate inhibition of phospholipase A2 activity from a variety of sources.{14107} There are no published studies of the pharmacological properties of lauric acid leelamide.

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