L-Phenylephrine (hydro<wbr>chloride)

L-Phenylephrine (hydrochloride)

CAT N°: 18619
Price:

From 48.00 40.80

L-Phenylephrine is an adrenergic ?1A receptor agonist (Ki = 1.4 µM) that demonstrates selectivity against the ?1B and ?1C receptor subtypes (Kis = 23.9 and 47.8 µM, respectively).{28120} By stimulating adrenergic ?1 receptors, L-phenylephrine can induce aortic smooth muscle contractions, although reported relative affinity and potency values in rabbit are 5-fold weaker compared to that of L-norepinephrine (Item No. 16673).{28119} This compound is frequently used to precontract smooth muscle in preparations designed to study the properties of various vasodilator agents.{28121,28122}

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