L-<wbr/>(+)-<wbr/>Ergothioneine

L-(+)-Ergothioneine

CAT N°: 14905
Price:

From 92.00 78.20

L-(+)-Ergothioneine is a naturally-occurring amino acid derived from histidine via hercynine.{23678} Ergothioneine is a stable antioxidant that scavenges and detoxifies free radicals and oxidants, increases intracellular thiol levels, controls nuclear factor-?B activation, and inhibits inflammatory gene expression.{23667,23665} In addition, it inhibits the peroxynitrite-dependent nitration of nitrotyrosine, blocks oxidative DNA damage and cell death, and prevents the formation of xanthine and hypoxanthine.{23667,23664,23668} Ergothioneine is transported by the organic cation/carnitine transporter 1, which has been linked with autoimmune diseases, including rheumatoid arthritis and Crohn’s disease.{23666}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (?S)-?-carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-1H-imidazole-4-ethanaminium, inner salt
  • Correlated keywords
    • 616-50-2 644-57-5 6330-63-8 natural products antioxidant oxidative stress injury inflammations NF-?B NF-kappaB NF-.kappa.B NF?b NFkB NFkappaB NF.kappa.B NF-kB autoimmune diseases arthritis free radicals ergothioneine amino acids histidine hercynine scavenges detoxifies oxidants intracellular thiol inhibitors inhibits inhibitions genes expression peroxynitrite nitrotyrosine DNA damage death xanthine hypoxanthine cation carnitine transporters 1 one OCTN1 OCTN-1 OCTN 1 one rheumatoid arthritis Crohn’s diseases trimethylbetaine 2-mercapto-histidine phytothioneine sympectothion thiasine thioneine thiotane
  • Product Overview:
    L-(+)-Ergothioneine is a naturally-occurring amino acid derived from histidine via hercynine.{23678} Ergothioneine is a stable antioxidant that scavenges and detoxifies free radicals and oxidants, increases intracellular thiol levels, controls nuclear factor-?B activation, and inhibits inflammatory gene expression.{23667,23665} In addition, it inhibits the peroxynitrite-dependent nitration of nitrotyrosine, blocks oxidative DNA damage and cell death, and prevents the formation of xanthine and hypoxanthine.{23667,23664,23668} Ergothioneine is transported by the organic cation/carnitine transporter 1, which has been linked with autoimmune diseases, including rheumatoid arthritis and Crohn’s disease.{23666}

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