L-Arginine-<sup>13</sup>C<sub>6</sub> (hydrochloride)

L-Arginine-13C6 (hydrochloride)

CAT N°: 9004088
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From 125.00 106.25

L-Arginine-13C6 is intended for use as an internal standard for the quantification of L-arginine (Item No. 23703) by GC- or LC-MS. L-Arginine is an amino acid and a precursor of nitric oxide (NO).{41250} L-Arginine is a substrate for NO synthase that is oxidized to form NO and L-citrulline. It enhances NO release induced by bradykinin (Item No. 37408) or A23187 (Item No. 11016) in porcine aortic endothelial cells.{41249} L-Arginine (30 and 300 mg/kg, i.v.) induces dilation of pial arterioles and increases cerebral blood flow in normotensive and spontaneously hypertensive rats.{41248} It also reduces infarct size by 35 and 28% in normotensive and spontaneously hypertensive rats, respectively, following middle cerebral artery occlusion.

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