L-Alanosine

L-Alanosine

CAT N°: 19545
Price:

57.00 48.45

L-Alanosine is an antibiotic derived from bacterium S. alanosinicus with antineoplastic activity in cells deficient in methylthioadenosine phosphorylase (MTAP) (mean IC50 = 4.8 ?M and 10 ?M in T-ALL and CAK-1 cells, respectively).{34433,34434} L-Alanosine inhibits adenylosuccinate synthetase to disrupt de novo purine biosynthesis, inhibiting cellular metabolism in MTAP-deficient tumor cells.{34435,34436,34437}

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