KT182

KT182

CAT N°: 15404
Price:

From 55.00 46.75

KT182 is a potent inhibitor of ?/?-hydrolase domain-containing protein 6 (ABHD6) with IC50 values of 1.7, 15.1, and 0.24 nM using Neuro2a membrane proteomes, recombinant ABHD6 in HEK293T cells, and Neuro2a cells in situ, respectively.{24855} Following administration of KT182 (1 mg/kg, i.p.) in mice, ABHD6 is inactivated in liver and brain extracts, suggesting that it is brain-penetrant, unlike the closely related compound KT203 (Item No. 14819).

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • [4-[3′-(hydroxymethyl)[1,1′-biphenyl]-4-yl]-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)-methanone
  • Correlated keywords
    • ABHD-6 a/B KT-182 203 Neuro-2A HEK-293T intraperitoneally intraperitoneal
  • Product Overview:
    KT182 is a potent inhibitor of ?/?-hydrolase domain-containing protein 6 (ABHD6) with IC50 values of 1.7, 15.1, and 0.24 nM using Neuro2a membrane proteomes, recombinant ABHD6 in HEK293T cells, and Neuro2a cells in situ, respectively.{24855} Following administration of KT182 (1 mg/kg, i.p.) in mice, ABHD6 is inactivated in liver and brain extracts, suggesting that it is brain-penetrant, unlike the closely related compound KT203 (Item No. 14819).

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