Isorhamnetin

Isorhamnetin

CAT N°: 16496
Price:

From 75.00 63.75

Isorhamnetin is a natural flavonol aglycone that is the 3-methyl metabolite of quercetin (Item No. 10005169). It has antioxidant activity and inhibits xanthine oxidase (IC50 = 0.40 µM).{9540} Isorhamnetin also competitively inhibits the human multidrug and toxic compounds extrusion transporter 1 (Ki = 0.32 µM), which has an important role in the excretion of xenobiotics at the kidney and liver.{27212} It has also been reported to potentiate the neurological actions of nerve growth factor, diminish the cardiotoxic impact of doxorubicin, and have beneficial anti-cancer effects.{27211,27210,27207,27208}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one
  • Correlated keywords
    • 98006-95-2 biochemical natural product antioxidant inhibitor oxidative injury flavonoid cancer cardiology neuroscience flavonol aglycone 3-methyl metabolitequercetin activity XO xanthine oxidase human multidrug toxic comounds extrusion transporter 1 one MATE1 excretion xenobiotic kidney liver neurological nerve growth factor cardiotoxic doxorubicin hydrochloride HCl anti-cancer anticancer C.I. 75680 C.I.75680 3′-methylquercetin 3′-methoxyquercetin
  • Product Overview:
    Isorhamnetin is a natural flavonol aglycone that is the 3-methyl metabolite of quercetin (Item No. 10005169). It has antioxidant activity and inhibits xanthine oxidase (IC50 = 0.40 µM).{9540} Isorhamnetin also competitively inhibits the human multidrug and toxic compounds extrusion transporter 1 (Ki = 0.32 µM), which has an important role in the excretion of xenobiotics at the kidney and liver.{27212} It has also been reported to potentiate the neurological actions of nerve growth factor, diminish the cardiotoxic impact of doxorubicin, and have beneficial anti-cancer effects.{27211,27210,27207,27208}

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