IP6K2 Monoclonal Antibody (Clone 4F10)

IP6K2 Monoclonal Antibody (Clone 4F10)

CAT N°: 10239
Price:

474.00 402.90

Inositol hexakisphosphate kinase 2 (IP6K2) is a cytoplasmic kinase that catalyzes the conversion of IP6 to diphosphoinositol pentakisphosphate in the presence of ATP.{22131} IP6K2 functions as a proapoptotic protein kinase.{22130} IP6K2 binds to tumor necrosis factor receptor-associated factor 2 and inhibits NF-?B signaling.{22139} Heat Shock Protein 90 regulates apoptosis through a normal physiological interaction with IP6K2 by inhibiting its catalytic activity.{22128} Thus, IP6K2 is a potential target for cancer therapeutics development.{22128}

Territorial Availability: Available through Bertin Technologies only in France

  • Correlated keywords
    • cytoplasmic kinases inositol phosphates IP6 InsP5PP proapoptotic tumor necrosis factor HSP90 TNF TRAF cancer HSPs 90
  • Product Overview:
    Inositol hexakisphosphate kinase 2 (IP6K2) is a cytoplasmic kinase that catalyzes the conversion of IP6 to diphosphoinositol pentakisphosphate in the presence of ATP.{22131} IP6K2 functions as a proapoptotic protein kinase.{22130} IP6K2 binds to tumor necrosis factor receptor-associated factor 2 and inhibits NF-?B signaling.{22139} Heat Shock Protein 90 regulates apoptosis through a normal physiological interaction with IP6K2 by inhibiting its catalytic activity.{22128} Thus, IP6K2 is a potential target for cancer therapeutics development.{22128}

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