Histone H2A (Xenopus, recombinant)
Histone H2A (Xenopus, recombinant)
Histone H2A is a core histone that forms a dimer with histone H2B.{46631} Two histone H2A/H2B dimers form an octameric...
€818.00
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From €146.00 €124.10
From €146.00 €124.10
IMP-1710 is an inhibitor of ubiquitin C-terminal hydrolase L1 (UCH-L1; IC50 = 38 nM in a fluorescence polarization assay) that contains an alkyne moiety for use in click chemistry reactions.{59849} It is selective for UCH-L1 over a panel of 20 deubiquitinating enzymes at 1 µM. IMP-1710 inhibits TGF-?1-induced fibroblast-to-myofibroblast transition (FMT) in primary lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis (IC50 = 740 nM). It has been used for labeling UCH-L1 in cell-based assays, followed by click reactions with azide-modified TAMRA and biotin capture reagents.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 5 mg, 500 µg |
|---|---|
| Shipping | dry ice |
| CAS number | 2383117-96-0 |
| Molecular formula | C23H19N5O |
| Smiles | O=C([C@H]1N(C#N)CCC1)N2C3=CC=CC(C(C4=C5)=CNC4=NC=C5C#C)=C3CC2 |
| Molecular weight | 381,4 |
| Custom code | 2933.99 |
| Formulation | A solution in ethanol |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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