IKD-8344

IKD-8344

CAT N°: 28194
Price:

548.00 465.80

IKD-8344 is a macrocyclic dilactone originally isolated from an actinomycete species and has diverse biological activities, including anticancer, antimicrobial, and anthelmintic properties.{52214,52215,52216} It is cytotoxic to L5178Y murine leukemia cells (IC50 = 0.54 ng/ml).{52214} IKD-8344 inhibits growth of the mycelial form of C. albicans (MIC = 6.25 ?g/ml) and potentiates the activity of polymyxin B (Item No. 14157) against the multidrug-resistant pathogenic bacterium B. cenocepacia.{52215,52216} It is active against T. spiralis in vitro and in vivo.{52214}

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