Idarubicin (hydro<wbr>chloride)

Idarubicin (hydrochloride)

CAT N°: 14176
Price:

54.00 45.90

Idarubicin is a 4-demethoxy analog of the leukemia therapeutic daunorubicin (Item No. 14159). Both are anthracycline antibiotics which intercalate in DNA and inhibit topoisomerase II, resulting in cancer cell cytotoxicity at low concentrations (IC50 = 20-120 nM for idarubicin).{22870,22872,22871} Idarubicin is effective in combination therapy for the treatment of different types of leukemia.{22873,22874}

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