(–)-Hyoscyamine

(–)-Hyoscyamine

CAT N°: 25644

(–)-Hyoscyamine is a tropane alkaloid, a muscarinic receptor antagonist, and an isomer of atropine (Item No. 12008).{43484,43485} (–)-Hyoscyamine inhibits the arterial depressor response induced by the muscarinic agonist methacholine in dogs.{43484} It is more effective than atropine at inhibiting EEG arousal in dogs following sciatic nerve stimulation when administered at doses of 0.5 and 1 mg/kg. (–)-Hyoscyamine induces convulsions in and is toxic to mice (LD50 = 95 mg/kg).{43485}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (?S)-?-(hydroxymethyl)-benzeneacetic acid, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
  • Correlated keywords
    • 1892-81-5 8000-07-5 28905-40-0 38411-64-2 47170-56-9 1891070-00-0 Cystospaz Daturine Duboisine Hyoscyamin Tropine tropate
  • Product Overview:
    (–)-Hyoscyamine is a tropane alkaloid, a muscarinic receptor antagonist, and an isomer of atropine (Item No. 12008).{43484,43485} (–)-Hyoscyamine inhibits the arterial depressor response induced by the muscarinic agonist methacholine in dogs.{43484} It is more effective than atropine at inhibiting EEG arousal in dogs following sciatic nerve stimulation when administered at doses of 0.5 and 1 mg/kg. (–)-Hyoscyamine induces convulsions in and is toxic to mice (LD50 = 95 mg/kg).{43485}

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