Hydroxy Pioglitazone

Hydroxy Pioglitazone

CAT N°: 28043
Price:

414.00 351.90

Hydroxy pioglitazone is a major metabolite of the peroxisome proliferator-activated receptor ? (PPAR?) agonist pioglitazone (Item Nos. 71745 | 22263 | 10028).{48274} It is formed from pioglitazone by the cytochrome P450 (CYP) isoform CYP2C8 with minor contributions from CYP3A4.{48275} Hydroxy pioglitazone binds to PPAR? (Ki = 1.2 ?M) and activates PPAR? in a time-resolved FRET (TR-FRET) assay (EC50 = 2.1 ?M).{48274}

We also advise you