Hydro<wbr/>cortisone 21-hemi<wbr/>succinate (sodium salt)

Hydrocortisone 21-hemisuccinate (sodium salt)

CAT N°: 18226
Price:

From 48.00 40.80

Hydrocortisone 21-hemisuccinate is a water-soluble form of the endogenous hormone cortisol. It can bind to glucocorticoid receptors, initiating the transcription of anti-inflammatory and immunosuppressive mediators and inhibiting proinflammatory cytokine activity (IC50 = 6.7 µM for IL-6).{29361} It is commonly used to supplement media for long-term epithelial or endothelial cell cultures and to differentiate pluripotent stem cells.{29362}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 21-(3-carboxy-1-oxopropoxy)-11?,17-dihydroxy-pregn-4-ene-3,20-dione, monosodium salt
  • Correlated keywords
    • 30678-79-6 2203-97-6 steroid stem cell research signal transduction receptor agonist nuclear intracelluar signaling inflammation immunology endocrinology biochemical cortisol hormone glucocorticoid anti-inflammatory antiinflammatory immunosuppressive culture derivative endogenous U4905 A-hydrocort Ahydrocort buccalsone corlan 21-sodium EF-corelan EFcortelan emi-corlin emicorlin flebocortide intracort nordicort oralsone solu-cortef solucortef soluglyc solu-glyc
  • Product Overview:
    Hydrocortisone 21-hemisuccinate is a water-soluble form of the endogenous hormone cortisol. It can bind to glucocorticoid receptors, initiating the transcription of anti-inflammatory and immunosuppressive mediators and inhibiting proinflammatory cytokine activity (IC50 = 6.7 µM for IL-6).{29361} It is commonly used to supplement media for long-term epithelial or endothelial cell cultures and to differentiate pluripotent stem cells.{29362}

We also advise you