HS-173

HS-173

CAT N°: 19156
Price:

From 55.00 46.75

HS-173 is an imidazopyridine analog that acts as a PI3K? inhibitor with an IC50 value of 0.8 nM.{31012} It demonstrates antiproliferative activity in T47D, SK-BR-3, and MCF-7 cells with IC50 values of 0.6, 1.5, and 7.8 ?M, respectively.{31012} HS-173 is reported to induce apoptosis by arresting the cell cycle at the G2/M phase and by activating caspases.{31013,31014} It has also been shown to block VEGF-induced angiogenesis both in vitro and in vivo.{31013}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 6-[5-[(phenylsulfonyl)amino]-3-pyridinyl]-imidazo[1,2-a]pyridine-3-carboxylic acid, ethyl ester
  • Correlated keywords
    • HS173 PI3K? PI3Ka SKBR3 MCF7 G2M phosphatidylinositol 3-kinase PI3K SKBR-3 SK-BR3 anti-proliferative T-47F T-47-D T47-d
  • Product Overview:
    HS-173 is an imidazopyridine analog that acts as a PI3K? inhibitor with an IC50 value of 0.8 nM.{31012} It demonstrates antiproliferative activity in T47D, SK-BR-3, and MCF-7 cells with IC50 values of 0.6, 1.5, and 7.8 ?M, respectively.{31012} HS-173 is reported to induce apoptosis by arresting the cell cycle at the G2/M phase and by activating caspases.{31013,31014} It has also been shown to block VEGF-induced angiogenesis both in vitro and in vivo.{31013}

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