Hexestrol

Hexestrol

CAT N°: 29003
Price:

From 48.00 40.80

Hexestrol is a synthetic non-steroidal estrogen receptor ligand that binds to estrogen receptor ? (ER?) and ER? (Kis = 0.06 and 0.06 nM for the human and rat receptors, respectively).{23592} It inhibits rat liver microsomal and ox brain phospholipid liposomal lipid peroxidation (IC50s = 1.5 and 2.75 ?M, respectively).{45569} It also inhibits porcine microtubule assembly and induces disassembly of preformed microtubules when used at concentrations of 50 and 100 ?M, respectively, in a cell-free assay.{45571} Hexestrol (25 mg/animal) induces kidney tumors in male Syrian hamsters.{45570}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • rel-4,4?-[(1R,2S)-1,2-diethyl-1,2-ethanediyl]bis-phenol
  • Correlated keywords
    • Cycloestrol Erythrohexestrol Estrifar Estronal Extra-Plex ExtraPlex Hexanoestrol Hexestrofen Hexron Hormoestrol Mesohexestrol NSC9894 Sinestrol Synestrol Synoestrol Synthovo Syntrogene nonsteroidal ER-? ?
  • Product Overview:
    Hexestrol is a synthetic non-steroidal estrogen receptor ligand that binds to estrogen receptor ? (ER?) and ER? (Kis = 0.06 and 0.06 nM for the human and rat receptors, respectively).{23592} It inhibits rat liver microsomal and ox brain phospholipid liposomal lipid peroxidation (IC50s = 1.5 and 2.75 ?M, respectively).{45569} It also inhibits porcine microtubule assembly and induces disassembly of preformed microtubules when used at concentrations of 50 and 100 ?M, respectively, in a cell-free assay.{45571} Hexestrol (25 mg/animal) induces kidney tumors in male Syrian hamsters.{45570}

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