Heronamide C

Heronamide C

CAT N°: 23644
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From 365.00 310.25

Heronamide C is a polyketide macrolactam antifungal agent produced by marine Actinomycetes.{40465} It inhibits the growth of and induces abnormal accumulation of cell wall material in wild-type fission yeast cells (MIC = 0.13-0.28 ?M). Heronamide C lacks activity against Gram-positive bacteria and human HeLa and MDA-MB-231 cancer cell lines.{40466} However, it induces reversible morphological changes, including formation of large intracellular structures, in HeLa cells at a concentration of 20 ?M.

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