Helenalin

Helenalin

CAT N°: 17050
Price:

761.00 646.85

Helenalin is a sesquiterpene lactone first isolated from various species of Arnica. It has anti-inflammatory effects, most notably by inhibiting gene expression mediated by NF-?B at doses from 1 to 20 µM.{27838,24738} Like other sesquiterpene lactones, helenalin can modify sulfhydryl groups of cysteine residues and it alkylates these groups on the p65 subunit of NF-?B.{27838} It also suppresses the proliferation of cancer cells through multiple mechanisms, including the prevention of signaling through NF-?B.{27836,20972,27837} Helenalin has antibacterial and anti-protozoal activities.{27839,27840}

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