Hecogenin Acetate

Hecogenin Acetate

CAT N°: 25977
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From 92.00 78.20

Hecogenin acetate is a steroid sapogenin and an acetylated form of hecogenin (Item No. 21372) that has anthelmintic and antinociceptive properties.{42489,42490,42491} It reduces the percentage of mobile larvae in goat fecal cultures containing Haemonchus, Oesophagostomum, and Trichostrongylus nematodes (EC50 = 0.49 mg/ml).{42489} Hecogenin acetate (5, 10, or 20 mg/kg, i.p.) inhibits development of mechanical hyperalgesia induced by carrageenan, TNF-?, dopamine (Item No. 21992), and prostaglandin E2 (PGE2; Item No. 14010) in mice.{42490} It also increases latency to tail withdrawal in the tail flick test and has no effect on motor performance in the rotarod test in mice when administered at a dose of 40 mg/kg.{42491}

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