€615.00 €522.75
Human chorionic gonadotropin (hCG) is glycoprotein hormone secreted during pregnancy that has important roles in the maintenance of pregnancy.{52901,52902} It exists as a heterodimer that is composed of two subunits, hCG? and hCG?, that are subject to glycosylation, generating a variety of glycosylated hCG variants that have distinct biological functions.{52903,52904} The expression of genes encoding hCG? and hCG? are regulated by a variety of hormones, growth factors, and cytokines.{52904} It is secreted by placental trophoblasts during early pregnancy and serum hCG levels peak from gestational weeks 7 to 10.{52901} hCG has numerous roles in pregnancy, including stimulating production of progesterone from the corpus luteum and promoting angiogenesis of uterine vasculature and the growth of fetal organs.{52905} Urinary hCG levels have been commonly used in the determination of pregnancy.{52901} Increased serum, urinary, or tumor levels of hCG? have been found in patients with a variety of cancers, including bladder, lung, cervical, or ovarian cancer, and are associated with poor prognosis.{52906} Cayman’s hCG Rabbit Monoclonal Antibody can be used for ELISA, immunohistochemistry (IHC), and Western blot (WB) applications. This antibody recognizes the hCG? subunit in both the monomeric and hCG?? heterodimeric forms.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 100 µl |
|---|---|
| Shipping | dry ice |
| Molecular weight | 0 |
| Host | Rabbit |
| Antigen | Native hCG protein purified from human urine |
| Clone | RM330 |
| Isotype | IgG |
| Application(s) | ELISA, IHC, WB |
| Formulation | 100 µl of protein A-affinity purified monoclonal antibody |
| Custom code | 3822.19 |
| UNSPSC code | 12352203 |
Cayman Chemical’s mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.
Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.
Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009
Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.
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