H-<wbr/>9 (hydro<wbr>chloride)

H-9 (hydrochloride)

CAT N°: 13312
Price:

From 42.00 35.70

The H series isoquinolinesulfonamide protein kinase inhibitors are widely used to block signaling pathways in order to elucidate mechanisms of cellular regulation and signal transduction. H-9 (hydrochloride), an isoquinolinesulfonamide protein kinase inhibitor, is a competitive inhibitor of PKC, PKG, and PKA with Ki values of 18, 0.87, and 1.9 µM, respectively.{16079} H-9 (hydrochloride) has been used to reduce the cAMP-mediated excitatory response to serotonin in C. elegans enteric neurons{17222} and to inhibit PKA-mediated phosphorylation in a rat seizure model.{17221}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-(2-aminoethyl)-5-isoquinolinesulfonamide, dihydrochloride
  • Correlated keywords
    • proteins kinases inhibitors inhibits inhibitions PKCs PKAs PKGs cGMPs cAMPs signal transductions competitive potent PKA-mediated mediated phosphorylation 84468-17-7
  • Product Overview:
    The H series isoquinolinesulfonamide protein kinase inhibitors are widely used to block signaling pathways in order to elucidate mechanisms of cellular regulation and signal transduction. H-9 (hydrochloride), an isoquinolinesulfonamide protein kinase inhibitor, is a competitive inhibitor of PKC, PKG, and PKA with Ki values of 18, 0.87, and 1.9 µM, respectively.{16079} H-9 (hydrochloride) has been used to reduce the cAMP-mediated excitatory response to serotonin in C. elegans enteric neurons{17222} and to inhibit PKA-mediated phosphorylation in a rat seizure model.{17221}

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